Shelley and Vitality, now in paperback and with a new Preface, reassesses Percy Shelley's engagement with late eighteenth- and early nineteenth-century science and medicine,
specifically his knowledge and use of theories on the nature of life presented in the debate between surgeons John Abernethy and William Lawrence. Ruston presents new biographical information
to link Shelley to a medical circle and St Bartholomew's Hospital in London. In poems such as Prometheus Unbound, Adonais, and the Defence of Poetry, Shelley employs the vocabulary and ideas
of this new science to express social, political and poetic questions and ideals. The medical search for a principle of life is shown to emerge from the political challenges of the day and to
confront issues which are characteristically Shelleyan: the desired selflessness of the Romantic subject, sensibility, mutability, and the necessity of repositioning humankind in a newly
conceived, active universe. The Shelley who emerges from this study is a more consistently materialist thinker than is usually acknowledged. Making use of rare books and manuscripts, Shelley
and Vitality will be of interest to students and scholars of Shelley and the links between science and literature.